B组维生素和矿物质是一个已在护发产品应用的有效成分理想组合，以验证效 果。他们供应头发生长所需的营养，改善头皮状况，提高了头发生长的协同效应。 • 铜肽：5α-还原酶 I及II型抑制，刺激细胞外基质合成，刺激血管新生。 • 硒：拮抗剂重金属，自由基灭活，加强组织弹性，预防头皮屑。 ‧ 锌，维生素B6：抑制双氢睾酮DHT的形成，增强免疫功能的头发生长刺 激。 ‧ 生物素：供应营养给头发，皮肤和指甲的健康，提高弹性，促进头发生 长，对保护干燥,头发角质层增厚的实际，增头发的直径。 ‧ 地塞米松泛醇 ：皮脂溶解，防止头皮屑，水化作用，增加透气性，并 促进整个头皮外的交流障碍。 <References> T. Takahashi， T， Kamiya， A， Hasegawa andY. Yokoo， "Procyanidin Oligomers selectively and intensively promote proliferation of mouse hair epithelial cells in vitro and activate hair follicle growth in vivo:' J Invest. Dermatol. (1999) 112-310-316 T. Takahashi， A. Kamimura， M，Kagoura， M. Toyoda and M. Morohashi. "Investigation of the topical application of procyanidin oligomers from apples to identify their potential use as a hair-growing agent:' JCD Vol. 4 issue 4 Page 245-2005 Dee A. Kamimura，T. Takahashi， M.Morohashi， Y. Takano. "Procyanidin oligomer counteract TGF- bl and TGF-b2-induced apotosis in hair epithelial cells" Skin pharm. phys， 19: 259 -265, 2006 Lintner， Karl (Rambouill帥， FR). Tosmetic and dermopharmaceutical compositions for skin prone to acne. United States patent 7182963， Sederma (FR)， 02/27/2007 Jahoda CA， Mauger A， Bard S， Sengel P. Thanges in fibronectin， laminin and type IV collagen distribution relate to basement membrane restructuring during the rat vibrissa follicle hair growth cycle:' J Anat. 1992 Aug， 181，47-60 Giner-Larza et al. Oleanolic acid， a 3-oxotriterpene from Pistacia， inhibits leukotriene synthesis and has anti-inflammatory activity:' Eur， J Pharmacal (2001) 428137-43 Zhang YH， Park YS， Kim TJ， Fang LH， Ahn HY， Hong JT， Kim Y， Lee CK， Yun YP. Endothelium-dependent vasorelaxant and anti proliferative effects of apigenin:' Gen Pharmacal. 2000 De亡，Dee. 35(6) 341-7 Sugimoto Y， Lopez-Solache I， Labrie F， Luu-The V. "Cations Inhibit specifically type I Sa-reductase found in human skin. J Invest. Dermatol. (1995)lO4775-778 Orentreich N， Berger Ra. "Selenium dis叫fide shampoo， its influence on hair growth and the follicular cycle:' Arch Dermatol. 1964 Jul， 90， 76-80 Allgood VE， Cidlowski JA.“Vitamin B6 modulates transcriptional activation by multiple members of the steroid hormone receptor superfamily:' J BioI. Chem. 1992 Feb. 267(6) 3819-24
